| Turkish Journal of Cancer |
| 2003, Volume 33, Number 1, Page(s) 40-50 |
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| Retrospective evaluation of operated stage I breast cancer patients |
| BERNA ÖKSÜZOĞLU, NİLÜFER GÜLER, EŞMEN BALTALI, AZİZ KARAOĞLU, YAVUZ ÖZIŞIK, KADRİ ALTUNDAĞ, GÜLTEN TEKUZMAN |
| Hacettepe University Faculty of Medicine, Department of Medical Oncology, Ankara-Turkey |
As there is no national screening programme in our
country, information about stage I breast carcinoma is
limited. In this study, 131 stage I breast cancer patients
followed between April 1989 and March 2001 at our
department, were retrospectively evaluated. Median age
was 49 (range: 26-77). Painless breast mass was the
most common symptom (75%). Tumor size was larger
than 1 cm in 66% of the patients. Seven percent of the
patients had no adjuvant therapy, 43% had adjuvant
tamoxifen and 50% had adjuvant chemotherapy ± tamoxifen.
CMF combination (± tamoxifen) was the most common
(71%) adjuvant chemotherapy regimen. Median
follow-up period was 43 (range: 5+-148+) months. During
the follow-up period, 1 patient had local recurrence and
distant metastases, 3 had distant metastasis, and 5
patients (3.8%) had metachronous breast carcinoma.
Two patients died with distant metastasis. Median disease
free survival and median overall survival were not reached.
Five-year disease free survival was 97% and, 5-year
overall survival was 98.5%. Follow-up period was short
and long-term follow-up is necessary for better analysis.
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