Sarcomatoid carcinomas are rare and aggressive tumors composed of both epithelial and mesenchymal elements.Our case is a 39 year old man who was hospitalized for mechanical bowel obstruction. Histopathological examination showed typical adenocarcinomatous areas admixed with sarcomatous areas and “sarcomatoid carcinoma of the colon” was diagnosed. Immunohistochemistry revealed strong positivity for cytokeratin and EMA in adenocarcinomatous areas and also in most of the cells of the sarcomatous areas.The patient is alive 4 months after surgery without evidence of recurrence. To our knowledge, there were only 8 cases of sarcomatoid carcinoma of the colon reported to date in the literature. [Turk J Cancer 2005;35(3):138-140]