| Turkish Journal of Cancer |
| 2008, Volume 38, Number 1, Page(s) 020-025 |
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| Results of transthoracic esophagectomy following chemoradiation in locally advanced esophageal cancer |
| HASAN FEVZİ BATIREL1, CENGİZ GEMİCİ2, BEDRETTİN YILDIZELİ1, TUNÇ LAÇİN1, ASLI GÜL AKGÜL1, SERDAR EVMAN1, HALE BAŞAK ÇAĞLAR4, MAHMUT İLHAN3, MUSTAFA YÜKSEL1 |
1Marmara University Faculty of Medicine, Department of Thoracic Surgery, İstanbul 2Kartal Lütfü Kırdar Teaching and Research Hospital, Department of Radiation Oncology, İstanbul 3Yüzüncü Yıl University Faculty of Medicine, Department of Medical Oncology, Van 4Marmara University Faculty of Medicine, Department of Radiation Oncology, İstanbul-Turkey |
We investigated patients treated with chemoradiation and
subsequent esophagectomy. 10 patients were treated between
2004-2007. The chemoradiation regimen was concurrent
4 - 0 Gy radiation with cisplatin and -fluorouracil.
Average age was 8 (31-74, 5 females). Clinical stages
were T3-4N0-1M0. 9 patients completed the curative or
neoadjuvant chemoradiation regimen. Pathologies were
squamous cell (n=9) and adenocarcinoma (n=1). All patients
underwent esophagectomy via a right thoracic approach,
followed by laparotomy and cervical incision. There
was no postoperative mortality. 7 patients had complications,
4 of them were major. Postoperative stages were
T2N0 (n=3), T3N0 (n=3), T2N1 (n=1) and T3N1 (n=3).
One patient died due to local and distant recurrence. Two
patients (>70 years) died of non-cancer related causes at
2 and 8 months. Seven patients are alive without disease,
3 of them at 3 , 19 and 18 months. Esophageal resection
following concurrent chemoradiation is a high risk procedure
that can be applied in well selected patients. [Turk J
Cancer 2008;38(1):20-25 ]
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