| Turkish Journal of Cancer |
| 2008, Volume 38, Number 4, Page(s) 190-193 |
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| Relapse of testicular cancer after 15 years |
| SERCAN AKSOY1, HAKAN HARPUTLUOĞLU1, SAADETTİN KILIÇKAP1, BÜLENT AKDOĞAN2, HUSEYİN ABALI3, MUSTAFA ERMAN1 |
1Hacettepe University, Institute of Oncology, Department of Medical Oncology, Ankara-Turkey 2Hacettepe University, Faculty of Medicine, Department of Urology, Ankara-Turkey 3Ankara Numune Training and Research Hospital, Department of Medical Oncology, Ankara-Turkey |
The introduction of cisplatin-based chemotherapy into
clinical practice has resulted in a substantial improvement
of relapse-free and long-term survival of patients with
testicular germ cell tumors. Late relapse (LR) of testicular
cancer has recently been described as a unique entity. It
is currently defined as tumor recurrence more than 2 years
after complete remission following primary treatment,
including chemotherapy. The incidence ranges from 2 to
6%, with a median relapse-free interval of 5.4-7.1 years
from the initial treatment. Authors report a case of nonseminomatous
germ cell tumor of the testis that recurred
15 years after the completion of first-line therapy. Though
a few such late relapses have been observed, this
condition remains extremely rare. Although the majority
of recurrences are encountered in the first 2 years after
treatment and later recurrences are rare, their time-course
and pattern have implications for long-term follow-up.
[Turk J Cancer 2008;38(4):190-193]
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