Breast cancer is the most common cancer in women. The most common histological type is infiltrating ductal carcinoma. Lobular, papillary, mucinous and medullary types have relatively lower incidence. Primary squamous cell carcinoma (SqCC) of the breast is a rare disorder[]. Although approximately 100 cases of SqCC of the breast have been documented in the literature, there are only few series documenting the management and clinical outcome of these tumors. The treatment principles are controversial and more information about SqCC of the breast is needed. Herein we report a 64-year-old woman with primary SqCC of the breast who was treated with cisplatinum containing chemotherapy. [Turk J Cancer 2009;39(1):26-27]